Zylkene Plus is a long-term calming supplement with a dual-action formula to promote relaxation in pets over longer periods. 

The behavior supplement includes alpha-casozepine and white fish muscle hydrolysate, which is naturally rich in bioactive marine peptides and supports adaptation, resilience, and cognitive function. 

Zylkene Plus is: 

• Made with high-quality ingredients
• Backed by real-world evidence¹
• Lactose free
• Non-sedating
• Proven palatability and ease of administration²

Zylkene Plus helps promote calm and relaxed behavior when a pet’s routine is altered in situations such as: 

• A new baby
• A new pet
• Moving
• Left home alone 

Zylkene Plus carries the quality seal of the National Animal Supplement Council. To display the NASC Quality Seal on our products, we undergo regular and rigorous audits to ensure we’re manufacturing only the highest-quality supplements for pets.

Capsules can be administered once daily, whole or opened. Can be given during or after mealtime. 

Zylkene Plus 225mg:

• Dogs 22-32 lbs: 1 capsule daily
• Dogs 33-65 lbs: 2 capsules daily
• Cats: 1 capsule daily or as recommended by a veterinarian 

Zylkene Plus 450mg:

• Dogs 33-65 lbs: 1 capsule daily
• Dogs 66-132 lbs: 2 capsules daily

Zylkene Plus is available in 30-count bottles.

Zylkene Plus is available from veterinarians, in stores, and from online retailers.

_{1. Porcheron, G., Bodet, M., Poiron, K., Brault, J., Massal, N., Roy, O., & Fantini, O. (2023). Supplementation Effects of an Alpha-Casozepine and White Fish Muscle Hydrolyzed Complementary Feed on Canine Separation-Related Disorders and Quality of Life of Dogs and Their Pet Caregivers. Open Journal of Veterinary Medicine, 13(6), Article 6.} 

_{2. Data on file, Vetoquinol.}

pH•notix helps streamline appointments by quickly breaking down ear wax and debris without requiring rinsing.

pH balanced

• pH•notix is medication’s favorite sidekick. Clean, dry ears can improve the overall efficacy of ear care.
• Some ear medications require a neutral pH to work most effectively. Tromethamine serves as a neutral buffer in pH•notix’s formula, which allows it to be used before application of most medicated treatments.

Fast action

• One-step cleaning. There is no need to irrigate ears after pH•notix application.
• The water-based formula doesn’t require rinsing. After application, its hydrating agent helps soothe and moisturize the ear canal.
• Quick ear cleaning allows you to rapidly move on to treatments if necessary.

Ideal for use in problem-prone ears

• Two ceruminolytic agents provide lysing action that disrupts the integrity of earwax and emulsifies debris to expedite the cleaning process.
• Lipacides help modulate sebum production and restore a healthy ear environment.

To clean and help remove wax from the ears of cats and dogs as part of a routine hygiene program. For the maintenance of healthy ears. pH•notix is pH balanced and paraben-free.

Shake before use.

1. Fill the ear canal with pH•notix.
2. Massage gently from bottom to top to help loosen and remove the debris.
3. Allow pet to shake head.
4. Wipe off any excess product with a cotton ball. Do not use a cotton swab.
5. Repeat the procedure if the ear is very dirty. Use 1 or 2 times a week, if needed, or as recommended by a veterinarian. Can be used before application of certain medicated treatments as directed by your veterinarian.
6. Rinse the applicator with tap water after use.

• Do not use in clean ears
• Do not use if eardrum is ruptured or suspected to be ruptured

For use in animals with intact eardrums. If any problems occur, stop the application and consult a veterinarian.

AVOID CONTACT WITH EYES.

pH•notix is available in a 4 oz. bottle with a standard applicator tip and a long, flexible plastic applicator.

Veterinarians can request pH•notix from their Vetoquinol representative or preferred distributor.

Flexadin Advanced promotes joint health in horses by targeting the immune system. Undenatured type II collagen has been clinically proven to be more effective than glucosamine and chondroitin.* Its unique, patented collagen ingredient helps reduce joint discomfort related to normal daily activity and supports joint integrity.

Flexadin Advanced is more than a supplement! It has been specifically formulated to:

• Help enhance a horse’s normal repair of cartilage and joints
• Help reduce joint discomfort related to exercise or normal daily activity and improve activity levels
• Help maintain joint mobility and flexibility
• Help support the structural integrity of joints
• Support a healthy inflammatory response

Initial Administration:
For horses and ponies 100 - 2500 lbs.: 1½ scoops (15 g)
Administer once daily for 12 weeks.

Maintenance Administration:
For horses and ponies 100 - 2500 lbs.: 1 scoop (10 g)
Administer 1 scoop (10 g) once daily.

Flexadin Advanced for horses is available in a 1.32 lbs. canister.

Flexadin Advanced for horses is available from veterinarians and online retailers.

* Based on a 150-day clinical study comparing [80 mg, 120 mg, or 160 mg undenatured type II collagen] to 5.4 g glucosamine and 1.8 g chondroitin (Gupta et al, Journal of Veterinary Pharmacology and Therapeutics, 2009).

UC•II^® is a Lonza trademark.

A pet’s life is full of new people, new situations, and new challenges. With Zylkene, pets can find balance when life gets stressful.

Zylkene is a behavior supplement that helps dogs and cats relax, adapt to new locations, or cope with challenging situations — without making them drowsy.

Zylkene is:

• Clinically proven to help relieve stress without drowsy side effects
• Veterinarian recommended to help pets cope with challenging situations like thunderstorms, car rides, separation, and more
• Made with natural ingredients that are easy on sensitive stomachs with a lactose- and preservative-free formula
• Contains alpha-casozepine, a natually occurring milk protein found in cow's milk

When to use Zylkene:

• New places. Whether a pet is visiting the groomer, the vet, or moving to a new home, Zylkene can help them stay calm as they adjust to new environments. It is clinically proven to help pets cope with challenging situations without drowsy side effects.
• New situations. Fireworks, thunderstorms, and travel: few things are more stressful to pets. That’s why Zylkene is the perfect supplement to help pets stay calm without sedation, which makes new situations easier for them — and for owners.
• New people. Is company coming over? New baby in the house? With Zylkene, your pets can calmly adjust to new additions to the family — or just friends coming over to visit – without stressing out about it.

Zylkene can be administered once daily, whole or opened. Can be given during or after mealtime. It’s the perfect supplement to help pets face life’s challenges.

Administer 1-2 days before the anticipated event. Some animals may need earlier administration (5-7 days)

Zylkene is available in 14-count packages, 30-count bottles, and 120-count bottles.

Zylkene is available from veterinarians and online retailers.